A 67-year-old man who had been taking turmeric supplements three times a day to manage workout-related inflammation was hospitalized with an abscess and small intestine perforation. He questioned whether excess turmeric could have caused his medical condition.
Turmeric, a plant in the ginger family native to India, has been used as a spice for over 4,000 years. Its main active compound, curcumin, is known for anti-inflammatory and antioxidant properties. Traditional Chinese, Indian, and Thai medicine have long included turmeric for its potential health benefits. In recent years, it has gained popularity in alternative medicine in the United States.
Curcumin can interfere with certain biochemical pathways involved in inflammation by blocking signaling molecules that contribute to joint pain and swelling. This property has led to increased interest in curcumin as a possible aid for managing chronic low-grade inflammation and oxidative stress associated with metabolic disease.
However, researchers note that curcumin is poorly absorbed when taken orally. To improve absorption—known as bioavailability—supplements often add substances like piperine (from black pepper) or dietary fat.
Although turmeric and curcumin may offer benefits, excessive use can cause gastrointestinal symptoms such as stomach discomfort, indigestion, nausea, loose stools, and diarrhea. “That said, there is no credible evidence that this would lead to an intestinal perforation or abscess,” according to UCLA Health Sciences Media Relations. The statement adds: “These are serious conditions that typically arise from infection, obstruction, reduced blood flow or underlying disease. Also, an abscess or an intestinal perforation would take far longer to develop than a few weeks of turmeric use.”
The response continues: “When a serious medical event occurs with, or closely follows, a change in routine, like adding a supplement, it is understandable to infer a connection. Based on what we know about turmeric and curcumin and the timing in your case, this connection seems unlikely. They are probably not the direct cause of your intestinal issues.” The doctors also advised caution: “Because turmeric can affect bleeding risk and interact with certain medications, we urge you to let your medical care providers know you have been using it.”
Questions may be sent to Ask the Doctors at UCLA Health Sciences Media Relations.
