The U.S. Department of Energy (DOE) has announced new collaboration agreements with 24 organizations to advance the Genesis Mission, a national initiative that aims to use artificial intelligence (AI) for scientific discovery, national security, and energy innovation. This announcement follows President Trump’s Executive Order on removing barriers to American leadership in AI and is part of the America’s AI Action Plan, which seeks to reduce reliance on foreign entities and enhance U.S. scientific capabilities.
A White House meeting marked the launch of these public-private partnerships, bringing together industry representatives, Secretary of Energy Chris Wright, DOE Under Secretary for Science and Genesis Mission Director Dr. Darío Gil, and Michael Kratsios, Director of the White House Office of Science and Technology Policy.
“Today’s announcement of 24 new research partnerships is only the beginning, as we deliver on President Trump’s mandate to bring the entire scientific community, including companies, universities, non-profits, and Federal agencies, into the Genesis Mission,” said Assistant to the President and OSTP Director Michael Kratsios. “Harnessing cutting-edge AI for science will dramatically increase the productivity of American scientists and researchers. The Genesis Mission will help America’s scientists automate experiment design, accelerate simulations, and generate predictive models that will lead to breakthroughs in energy, manufacturing, drug discovery, and beyond.”
“Thanks to President Trump’s leadership, the Genesis Mission will be transformative for our country, uniting industry, academia, and our National Labs to deliver powerful and impactful scientific discovery and innovation,” said DOE Under Secretary for Science and Genesis Mission Director Dr. Darío Gil. “These agreements help advance President Trump’s Executive Order to build the national AI platform for scientific discovery and uplift the entire U.S. R&D ecosystem.”
The organizations involved have signed memorandums of understanding with DOE either after responding to a request for information or through ongoing projects with DOE or its National Laboratories related to the Genesis Mission. Any products developed under this mission are intended to be architecture-agnostic.
The participating organizations include Accenture; AMD; Anthropic; Armada; Amazon Web Services; Cerebras; CoreWeave; Dell; DrivenData; Google; Groq; Hewlett Packard Enterprise; IBM; Intel; Microsoft; NVIDIA; OpenAI; Oracle; Periodic Labs; Palantir; Project Prometheus; Radical AI; xAI; and XPRIZE.
DOE plans further meetings with private sector collaborators as well as academic institutions and philanthropic groups in order to broaden participation in the mission. The department continues to accept submissions for its open requests for information: “Partnerships for Transformational Artificial Intelligence Models” is open until January 14, 2026 while “Transformational AI Capabilities for National Security” remains open until January 23, 2026.
For more details about the Genesis Mission or partnership opportunities visit www.genesis.energy.gov or contact genesismission-partnerships@hq.doe.gov.
