President Donald Trump has announced the launch of the Genesis Mission, a national initiative led by the Department of Energy (DOE) aimed at advancing American science and innovation through artificial intelligence (AI). The mission is designed to enhance the United States’ technological leadership and competitiveness globally.
According to the Department of Energy, the Genesis Mission seeks to leverage current developments in AI and advanced computing to double productivity and impact in American science and engineering within ten years. The initiative aims to drive significant breakthroughs that support energy dominance, scientific discovery, and national security.
“Throughout history, from the Manhattan Project to the Apollo mission, our nation’s brightest minds and industries have answered the call when their nation needed them,” said U.S. Secretary of Energy Chris Wright. “Today, the United States is calling on them once again. Under President Trump’s leadership, the Genesis Mission will unleash the full power of our National Laboratories, supercomputers, and dataresources to ensure that America is the global leader in artificial intelligence and to usher in a new golden era of American discovery.”
The announcement follows President Trump’s earlier Executive Order focused on removing barriers for U.S. leadership in AI as well as his America’s AI Action Plan released this year. These efforts are intended to encourage innovation while reducing reliance on foreign sources for critical technologies.
Secretary Wright has appointed Under Secretary for Science Dr. Darío Gil to direct the initiative. The Genesis Mission will involve all 17 DOE National Laboratories along with partners from industry and academia. The project aims to build an integrated platform connecting supercomputers, AI systems, quantum technology, and scientific instruments across the country. Once operational, this platform is expected to become one of the most powerful scientific tools ever created by bringing together approximately 40,000 DOE scientists, engineers, technical staff members, and private sector collaborators.
The mission will address three main challenges:
– Achieving energy dominance through advanced nuclear technology, fusion research, and modernization of electrical grids using AI.
– Advancing discovery science by developing a robust quantum ecosystem with government investment and public-private partnerships.
– Ensuring national security by creating advanced AI technologies for defense purposes and maintaining safety standards for nuclear stockpiles.
Under Secretary for Science Dr. Darío Gil stated: “The Genesis Mission marks a defining moment for the next era of American science. We are linking the nation’s most advanced facilities, data, and computing into one closed-loop system to create a scientific instrument for the ages, an engine for discovery that doubles R&D productivity and solves challenges once thought impossible.”
Brandon Williams, Administrator of the National Nuclear Security Administration (NNSA), commented: “The Genesis Mission represents the next great chapter and an unparallelled opportunity for America’s scientific and national security leadership.
“Building on decades of innovation and collaboration across our national laboratories, NNSA will leverage AI, quantum computing, and advanced data analytics that will strengthen our deterrents and ensure the United States maintains an unmatched strategic edge over our adversaries. Under President Trump’s leadership, this mission will embody the very best of American ingenuity, turning science and innovation into security.”
Dr. John Wagner, Chair of the National Laboratory Directors’ Council added: “DOE’s National Laboratories are engines of discovery that keep the United States competitive and secure. The Genesis Mission unlocks the full potential of these institutions by giving our scientists and engineers tools to work at the speed of innovation. Our laboratories have always risen to meet the nation’s greatest challenges, and this initiative ensures we continue that legacy in the age of artificial intelligence.”


